EarlyTox Cardiotoxicity Kit

For researchers looking to identify cardiotoxic compounds, the EarlyTox™ Cardiotoxicity Kit allows you to screen more compounds earlier in drug discovery. Now you can prioritize leads and direct medicinal chemistry efforts sooner, improving productivity and reducing costs associated with extensive safety testing downstream.

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EarlyTox Cardiotoxicity Kit

The EarlyTox™ Cardiotoxicity Kit provides a fast, simple, and reliable fluorescence-based method for identifying cardiotoxic compounds in a biorelevant assay using stem-cell derived cardiomyocytes. Leveraging our proprietary masking technology with our novel calcium sensitive indicator, researchers can:

Eliminate cardiotoxic compounds and identify potential drug candidates
Measure 384 samples in minutes rather than hours
Minimize non-specific effect of dye on beat characteristics
Reduce well-to-well variation and improve data quality
Largest signal dynamic range available
Benchmark against three reference compounds: isoproterenol, sotalol and propranolol

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(2) Vials of Component A*
(1) Bottle of dilution buffer (Component B)
(1) Vial each of three reference compounds: isoproterenol, sotalol and propranolol

* Each reagent vial (Component A) is sufficient for 1 plate (96- or 384-wells). Each kit is sufficient for 2 plates.

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(2) Vials of Component A**
(1) Bottle of dilution buffer (Component B)
(1) Vial each of three reference compounds: isoproterenol, sotalol and propranolol

** Each reagent vial (Component A) is sufficient for 5 plates (96-, 384- or 1536-wells). Each kit is sufficient for 10 plates.

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