ForteBio Launches Dip and Read Ni-NTA Biosensor for Protein Analysis

May 31, 2012

PORT WASHINGTON, N.Y., May 31, 2012 — ForteBio®, a division of Pall Life Sciences (NYSE: PLL) and a leading supplier of label-free technology that accelerates the development of biotherapeutic and pharmaceutical products, today announced the introduction of its Dip and Read™ Ni-NTA biosensor for use on its Octet® and BLItz™instrumentation platforms. The new biosensor is pre-immobilized with novel nickel-charged tri-nitrilotriacetic (Tri-NTA) groups enabling an easy, rapid and direct method for quantitation and kinetic analysis of polyhistidine-tagged (HIS-tagged) biomolecules. “Nickel provides an excellent binding medium for the stable capture of HIS-tagged proteins as part of quantitation and characterization studies,” said Christopher Silva, ForteBio division’s vice president of marketing. “However, standard formats for using this medium have been cumbersome, time-consuming and expensive. Now, our new Ni-NTA biosensor enables scientists to quickly and easily analyze HIS-fusion proteins with unsurpassed ease of use and workflow efficiency.” The Ni-NTA biosensor is designed for use in buffer and diluted complex media. Each biosensor can also be regenerated up to 10 times via a standard low-pH protocol in as little as two minutes for various applications such as acquisition of replicate data (same ligand/analyte pair) and “bucket-based” screening applications. ForteBio’s Octet family of products is based on the company’s proprietary BioLayer Interferometry (BLI) technology. It incorporates disposable optical Dip and Read biosensors that measure multiple interactions in parallel, without the use of detection agents. For single-sample analysis, ForteBio recently launched its BLItz platform. The new platform revolutionizes the use of label-free protein analysis by making it more accessible and cost-effective for individual bench scientists in biotherapeutic discovery, process development and academic research.

About ForteBio

ForteBio is a division of Pall Life Sciences, a unit of Pall Corporation. ForteBio provides analytical systems to accelerate biotherapeutic drug discovery and development. These systems enable real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. ForteBio’s analytical capabilities enable significantly easier, faster and better characterization of drug candidates, thus providing greater value in drug development applications where existing methods have limitations in throughput, performance and cost. For more information, visit www.fortebio.com.

About Pall Life Sciences

Pall Life Sciences provides cutting-edge products and services to meet the demanding needs of customers discovering, developing and producing biotech drugs, vaccines and classic pharmaceuticals. Pall technologies are also used to collect and process blood components and help protect patients from hospital-acquired infections. The company’s membranes and membrane devices optimize detection and sample preparation in the drug research, clinical diagnostics, genomics, and proteomics markets. Pall is a leading provider of separation systems and single-use filtration and purification technologies to pharmaceutical and biotechnology companies to support faster development of new drugs and vaccines that are safer and require less energy and water to produce.

About Pall Corporation

Pall Corporation (NYSE: PLL) is a filtration, separation and purification leader providing solutions to meet the critical fluid management needs of customers across the broad spectrum of life sciences and industry. Pall works with customers to advance health, safety and environmentally responsible technologies. The company’s engineered products enable process and product innovation and minimize emissions and waste. Pall Corporation, with total revenues of $2.7 billion for fiscal year 2011, is an S&P 500 company with almost 11,000 employees serving customers worldwide. Pall has been named a “top green company” by Newsweek magazine. To see how Pall is helping enable a greener, safer, more sustainable future, follow us on Twitter @PallCorporation or visit www.pall.com/green.

Contact Information :
Gemma Milan
650-289-6800
gemma_milan@pall.com