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Come and meet our friendly local team at SLAS2019 in Washington, DC. Stop by our booth to find out about our latest developments in high-content and cellular imaging, cell line development and automation tools for use in your lab. SLAS2019 will provide a unique combination of education, access to innovative technologies and intelligent peer networking, delivering unmatched value for professionals and students looking to discover the latest life sciences technologies and how they can be applied to drive research objectives.
Phenotypic screening in 3D culture including ECM : Advantages and challenges
Speaker: Nathalie Maubon, HCS Pharma (CEO, CSO), Grégory Maubon, PhD, HCS Pharma (Digital Coordinator, CDO)
Monday, February 4, 12:30pm - 1:15pm
Walter E. Washington Convention Center l 143C
Cellular assay in 3D culture have shown many advantages to better mimic in vivo situations. Nevertheless, 3D technology used for phenotypic screening is often really simple, as in the use of ULA plates. But we can go further by using 3D technologies which allow reproduction of the microenvironment of a healthy or pathological organ of interest. During this talk, we will discuss how the cellular microenvironment impacts the proliferation and/or differentiation of cells. A few examples will be presented in oncology, CNS and metabolic diseases fields. High-Content Screening (HCS) devices, such as the ImageXpress® Micro Confocal system, are now fast enough and sensitive enough to allow image acquisition in 3D cellular models. Nevertheless, to go further, perceptions and processes need to be changed. We will highlight new, cutting-edge technologies, including virtual and augmented realities, deep learning and machine learning, and explain how these new technologies can be of benefit to phenotypic screening.
Streamlining workflows for single-cell cloning. Single-cell identification and productivity screening simplified.
Speakers: Brian Bordeau, Global Business Development Manager; Alison Glaser, Global Client Solutions Manager; and Constantine Radu, Global Proposal Manager, Advanced Workflow Engineering Solutions, Molecular Devices
Tuesday, February 5, 2:00pm-2:45pm
Walter E. Washington Convention Center l Room 144A
Biologics have seen tremendous growth in recent years, but their discovery and manufacturing remains costly and time-consuming. Single-cell cloning, critical in processes from early drug screening to manufacturing, has traditionally been inefficient. Increasing the process efficiency has been limited by the available technologies, published data, and trade secrets. This tutorial will explore the latest in technologies and published literature for scaling up single-cell cloning workflows.
Unique confocal imaging solution capable of imaging more than a million wells a week