Single-Cell Cloning

Single-Cell Cloning

Achieve superior monoclonal cell line development with our advanced single-cell cloning solutions

Single-Cell Cloning

Single-cell cloning is a laboratory technique used to isolate and grow individual cells to produce genetically uniform cell lines. This method ensures that each cell line originates from a single progenitor cell, which is crucial for applications requiring consistency and reproducibility, particularly in therapeutic protein production, drug development, and research studies. Traditional methods like limiting dilution cloning (LDC) are labor-intensive and inefficient, often requiring multiple rounds to achieve a high probability of clonality (PoC). Our CloneSelect® Imager provides reliable methods for imaging and analyzing mammalian cells, ultimately leading to high monoclonal colony yields and regulatory compliance. This tool is indispensable for industrial cell line development, enabling rapid, accurate, and efficient single-cell isolation and analysis.

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CloneSelect Imager

High-resolution imaging and analysis system for monoclonality assurance

The CloneSelect® Imager delivers high-resolution fluorescence imaging, and single-celll analysis to provide reliable evidence of monoclonality for regulatory compliance.

CloneSelect Imager CloneSelect Imager
  • Automated Colony Screening: Screens colonies with high precision, supporting high-throughput cell line development.
  • Advanced Fluorescence Imaging: Captures detailed images to confirm clonality, improving data reliability.
  • Seamless Workflow Integration: Easily integrates with the DispenCell system for a comprehensive single-cell cloning solution.
  • Customizable Analysis Settings: Offers flexible imaging and analysis options to meet specific research requirements.

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