Automation-enabled phenotypic profiling based on the Cell Painting assay

Simplified, user-friendly, automated workflow for phenotypic profiling based on the Cell Painting assay

Cell Painting assays are typically carried out at scale with multiple assay plates. The workflows can be time and labor intensive, taking several days to complete a screen. Here, we developed a complete automated workflow for the Cell Painting assay highlighting how the use of an automated workflow can be used for morphological profiling, with the added benefits of reduced hands-on time and user handling errors, with increased assay throughput.