Water immersion objectives can offer signal increases of up to 4X, which can help scientists see deeper into 3D and thick tissue samples at lower exposure times.
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Water immersion objectives provide an index of refraction similar to the media by using water as a conduit for the light path between the objective and the plated sample. Index matching decreases optical aberrations and enables our water immersion objectives to have a higher numerical aperture, as compared to air, which can improve lateral and axial resolution even deep into the media.