APPLICATION NOTE
Using a next-generation high-content screening platform and AI-analysis tools to increase insights
Accelerate drug discovery with high-resolution imaging and intelligent analysis using patient-derived organoids.
In this application note, we explore how the ImageXpress® HCS.ai System and IN Carta® Software were used to evaluate dose-dependent effects of anti-cancer compounds on patient-derived colorectal cancer organoids. By combining Deep Tissue Spinning Disk technology with QuickID™ Targeted Acquisition, we captured high-resolution images through thick 3D samples—focusing efficiently on regions of interest. Using AI-powered segmentation and machine learning classification, we quantified subtle morphological changes across hundreds of features, uncovering meaningful insights from complex, physiologically relevant models.
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Product family
Imaging
Product primary application
ImageXpress HCS.ai High-Content Screening System, IN Carta Image Analysis Software, MetaXpress High-Content Image Acquisition and Analysis Software, 3D Ready Organoid
CMP
701Rn00000iKijVIAS
Title
Using a next-generation high-content screening platform and AI-analysis tools to increase insights
Resource URL
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