APPLICATION NOTE
Toxicity evaluation using 3D mouse intestinal organoids
Automated 3D organoid assay for intestinal toxicity screening using AI-powered imaging
This application note presents an automated, AI-driven workflow for evaluating compound toxicity using 3D mouse intestinal organoids. The CellXpress.ai® Automated Cell Culture System enables consistent seeding and culturing, while the ImageXpress® HCS.ai High-Content Screening System captures high-resolution phenotypic changes. Machine learning tools in IN Carta® Image Analysis Software classify organoids as live or damaged and quantify toxicity effects across multiple markers.
This integrated approach streamlines complex 3D assays, delivering scalable, reproducible results for high-throughput drug screening.
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Product family
3D Biology
Product primary application
CellXpress.ai Automated Cell Culture System; IN Carta Image Analysis Software; ImageXpress HCS.ai High-Content Screening System; Lab automation for high-throughput plate-based assays; Intestinal Organoids; Drug Discovery and Development; Automated Cell Culture; AI machine learning and deep learning tools for cell image analysis
cmp
701Rn00000gQ7iRIAS
Title
Toxicity evaluation using 3D mouse intestinal organoids
Resource URL
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