DataXpress 2.0

Data analysis and management software for electrophysiology

DataXpress 2 Electrophysiology Data Management and Analysis System

DataXpress 2 is a data management and analysis system for electrophysiology data. By incorporating a SQL Server database with over 100 attributes, users can quickly query and sort information about their assays. The system's trial editing, analysis and graphing capability provides users with a comprehensive set of tools to analyze and interpret their data. DataXpress seamlessly integrates with the PatchXpress 7000A automated parallel patch clamp system. The powerful graphical macro editor for automated data analysis significantly reduces the time required to analyze electrophysiology data from the PatchXpress 7000A.

Powerful Database to Manage Electrophysiology Data

DataXpress 2 stores information using a variant of MDCStore, a database structure used in several Molecular Devices Corporation database applications. This architecture uses Microsoft SQL Server database and MDC File Server to efficiently manage information. Newly acquired data files are automatically parsed for their attributes, which are stored in the database. Raw data files are stored elsewhere on the network via MDC File Server. The SQL Server database serves as a hub from which data from multiple acquisition systems can flow, while multiple users are analyzing their data. With over 100 attributes that can be queried, users can rapidly search and sort the database for information about their assays. User permission levels and data sharing capability ensure that users can access only raw data and analysis results that they have permission to view and analyze. The use of an ODBC interface for the connection between DataXpress clients and server provides improved database connection reliability.

Comprehensive Electrophysiology Analysis Tools

To analyze electrophysiology data, DataXpress 2 features a comprehensive set of analysis tools. Using the now-integrated trial editing functions, users can adjust the baseline, perform arithmetic operations on trials, average, filter, time shift, and apply other signal conditioning functions to their data sets. Up to 18 different measurement types (e.g., peak amplitude, time of peak, mean current, and 15 other types) from up to eight different search regions within trials can be applied to recordings. DataXpress 2 provides an extensive selection of 16 different types of higher-level analysis, such as current/voltage, curve fitting, tools for IC50 and EC50 analysis, and effective concentration percentage. Information is conveniently displayed in a spreadsheet format for easy management and can be exported as comma separated value (CSV) or MS Excel files for further analysis. To facilitate interpretation, data can be visualized and graphically presented automatically as multiple plots, histogram plots, scatter plots, or line graphs. Both graphs and numerical results can be copied to the clipboard to include them in a presentation, in your lab notebook or in other documentation.

Automated Data Analysis using Graphical Macro Editor

Trial Editing and Analysis commands are recordable using the graphical macro editor of DataXpress 2. Macros are created as a sequence of dialog-configured commands, making them straightforward to create and edit. A window displays the macro steps in a tree format so it is always easy to see the details of your analysis. Multi-step Undo and Redo functionality allows you to experiment with analysis steps and see the results before saving the macros. The ability to run a macro while recording another allows the creation of complex macros from a library of commonly used sub-macros. Once saved, macros can be replayed and applied to new datasets to efficiently automate your data analysis. Macros can be stored and managed on a user basis and shared with other DataXpress users. A comprehensive set of sample macros, together with step-by-step tutorials on their use, is provided to help you get started with setting up your own customized analysis procedures.

Seamless PatchXpress 7000A Integration

DataXpress 2 seamlessly integrates with the PatchXpress 7000A system. The automatic DataXpress Importer parses PatchXpress 7000A data files and stores attributes in the SQL Server database, moves data files to the file storage location via MDC File Server, and stores information about compound additions and timing. By storing all the information about your assay, DataXpress 2 can recreate the sequence of events that occurred in an experiment.

Summary

DataXpress 2 is a data management and analysis system for electrophysiology data. By incorporating a SQL Server database with over 100 attributes, users can quickly query and sort information about their assays. The system's trial editing, analysis and graphing capability provides users with a comprehensive set of tools to analyze and interpret their data. DataXpress seamlessly integrates with the PatchXpress 7000A system and incorporates a powerful graphical macro editor for automated data analysis that reduces the time required to analyze electrophysiology data.