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OpusXpress Published Papers

Papers published using data from the OpusXpress Parallel Oocyte Voltage Clamp

  • The neuroprotective effect of 2-(3-pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a novel alpha7 ligand, is prevented through angiotensin II activation of a tyrosine phosphatase.  Marrero MB, Papke RL, Bhatti BS, Shaw S, Bencherif M.
    Journal of Pharmacology & Experimental Therapeutics  309(1):16-27 (2004).
  • Effects at a distance in alpha7 nAChR selective agonists: Benzylidene substitutions that regulate potency and efficacy.  Papke RL, Meyer EM, Lavieri S, Bollampally SR, Papke TA, Horenstein NA, Itoh Y, Porter Papke JK.
    Neuropharmacology  46(7): 1023-1038 (2004).
  • Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.  Papke RL, Porter Papke JK, Rose GM.
    Bioorganic & Medicinal Chemistry Letters  14(8): 1849-1853 (2004).
  • The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors.  Stokes C, Papke JK, Horenstein NA, Kem WR, McCormack TJ, Papke RL.
    Molecular Pharmacology  66(1): 14-24 (2004).
  • A single point mutation confers properties of the muscle-type nicotinic acetylcholine receptor to homomeric alpha7 receptors.  Placzek AN, Grassi F, Papke T, Meyer EM, Papke RL.
    Molecular Pharmacology  66(1): 169-177 (2004).
  • Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist.  Papke RL, Schiff HC, Jack BA, and Hornstein NA.
    Neuroscience Letters 378  (3):140-144 (2005).
  • Tyrosine residues that control binding and gating in the 5-HT3 receptor revealed by unnatural amino acid mutagenesis.  Darren L. Beene, Kerry L Price, Henry A Lester, Dennis A Dougherty, and Sarah CR Lummis.
    Journal of Neuroscience  24: 9097-9104 (2004).
  • Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor.  Amanda L. Cashin, E. James Petersson, Henry A. Lester, and Dennis A. Dougherty.
    Journal of the American Chemical Society  127: 350-356 (2005).