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Instruments
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Electrophysiology
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IonWorks Quattro
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Electrophysiology
Automated
IonWorks Quattro
PatchXpress 7000A
OpusXpress 6000A
Conventional
Amplifiers Intro
Innovative Uses
Data Acquisition Intro
Microelectrode Amplifiers
Axoclamp 900A
MultiClamp 700B
Axopatch 200B
Headstages & Holders
Model cells, Odd bits
Single-Cell Electroporator
Axoporator 800A
Data Acquisition
and Analysis
Digidata 1440A
CyberAmp 380
IonWorks Presentations
Webinars
Accelerating ion channel drug discovery with automated electrophysiology
2005 Automated Electrophysiology Users Meeting
Use of automated electrophysiology platforms for compound profiling at hERG K+ channels
Peter Miu, Amgen
hERG safety assay-integration into a high throughput ADME screening facility
Jayne Ford, Cyprotex
Positioning of IonWorks™ HT in ion channel drug discovery
Del Trezise, GSK
Compound screening against cardiac sodium channels with IonWorks HT using a native cell line
Qiang Lu, Wyeth
2004 UK Users Meeting Presentations
Applications of IonWorksHT in ion channel drug discovery and compound profiling
Derek J Trezise, GlaxoSmithKline
2004 US Users Meeting Presentations
Impact of high throughput electrophysiology in new drug discovery: role of the IonWorks HT System in drug safety testing and functional assay development
Arturo Picones, Ph.D., Exelixis, Inc.
Rapid evaluation of ion channel drug targets using IonWorks
Victor A. Panchenko, Ph.D., Vertex Pharmaceuticals
Applications of IonWorks HT for drug discovery: functional characterization of stable expressing hERG cell lines and as a screening tool for evaluating the cardiac liability of preclinical drug candidates
Heather Guthrie, Hoffmann-La Roche Inc.
Voltage-gated calcium channel assay development and optimization on IonWorks HT
Joseph G. McGivern, Amgen
A high-throughput electrophysiological assay for T-type Ca
2+
channels on IonWorks HT
Yi-xin Qian
1
, Nick Callamaras
2
, and Joseph G. McGivern
1
.
1
Amgen Inc.
2
Molecular Devices Corporation.
2003 Users Meeting Presentations
State dependent screening and Ionworks™. Assay development and implementation
Jeff Pfohl, Ph.D., Amphora
Development of novel high throughput patch clamp assays for ion channel targeted drug discovery
Laszlo Kiss, Ph.D., Merck Research Laboratories
Sodium channel pharmacology: a practical comparison of FLIPR, IonWorks HT and traditional whole-cell recording
James T. Limberis, Ph.D., Pharmacia
IonWorks
Literature & Downloads
Automated Ephys Users Meetings
Automated Electrophysiology Webinars
Customer Presentations
Technical Support
Cell Line and Cell Line Optimization
Comparison Charts
Automated Electrophysiology
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