IonWorks Presentations

Webinars

• Accelerating ion channel drug discovery with automated electrophysiology

2005 Automated Electrophysiology Users Meeting

• Use of automated electrophysiology platforms for compound profiling at hERG K+ channels
  Peter Miu, Amgen
• hERG safety assay-integration into a high throughput ADME screening facility
  Jayne Ford, Cyprotex
• Positioning of IonWorks™ HT in ion channel drug discovery
  Del Trezise, GSK
• Compound screening against cardiac sodium channels with IonWorks HT using a native cell line
  Qiang Lu, Wyeth

2004 UK Users Meeting Presentations

• Applications of IonWorksHT in ion channel drug discovery and compound profiling
  Derek J Trezise, GlaxoSmithKline

2004 US Users Meeting Presentations

• Impact of high throughput electrophysiology in new drug discovery: role of the IonWorks HT System in drug safety testing and functional assay development
  Arturo Picones, Ph.D., Exelixis, Inc.
• Rapid evaluation of ion channel drug targets using IonWorks
  Victor A. Panchenko, Ph.D., Vertex Pharmaceuticals
• Applications of IonWorks HT for drug discovery: functional characterization of stable expressing hERG cell lines and as a screening tool for evaluating the cardiac liability of preclinical drug candidates
  Heather Guthrie, Hoffmann-La Roche Inc.
• Voltage-gated calcium channel assay development and optimization on IonWorks HT
  Joseph G. McGivern, Amgen
• A high-throughput electrophysiological assay for T-type Ca²⁺ channels on IonWorks HT
  Yi-xin Qian¹, Nick Callamaras², and Joseph G. McGivern¹.
  ¹Amgen Inc. ²Molecular Devices Corporation.

2003 Users Meeting Presentations

• State dependent screening and Ionworks™. Assay development and implementation
  Jeff Pfohl, Ph.D., Amphora
• Development of novel high throughput patch clamp assays for ion channel targeted drug discovery
  Laszlo Kiss, Ph.D., Merck Research Laboratories
• Sodium channel pharmacology: a practical comparison of FLIPR, IonWorks HT and traditional whole-cell recording
  James T. Limberis, Ph.D., Pharmacia