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Cellular Imaging Comparison Chart

Molecular Devices high content imaging systems bring powerful cellular and sub-cellular analysis tools to the screening environment. Featuring industry-leading image analysis software and powerful database tools, the systems provide researchers with insights into how potential therapeutics affect multiple cellular processes.

Molecular Devices offers two platforms for high content imaging: ImageXpress® Micro and ImageXpress Ultra.

The ImageXpress Micro features a small footprint and utilizes an optional high-speed laser auto-focus option that allows for the acquisition of more than 50,000 wells/200 plates per day. The system is easily upgradeable to support full environmental control (CO2, humidity and temperature) as well as advanced liquid handling for simultaneous liquid addition and reading.

The ImageXpress Ultra is a true point-scanning confocal system that features laser-based illumination for sequential or simultaneous imaging.

  ImageXpress Ultra ImageXpress Micro
Environmental control option   X
Liquid handling option1  
Fixed cell imaging X X
Transmitted light option2   Brightfield /
phase contrast
Smaller footprint X X
Detection PMTs CoolSNAPES (standard)
CoolSNAPHQ (option)
Image-based auto-focus   X
High-speed laser auto-focus X option
Robotics/automation option X X
Light source 2 to 4 excitation lasers 300W xenon arc lamp
Automated filter cube changer X X
Automated Z focus X X
Automated objective changer X X
Air objective compatibility 4X - 100X 2X - 100X
Oil-immersion objective compatibility 40X-100X 40X-100X
Automated X-Y sample stage X X
Imaging plate compatibility 6-, 12-, 24-, 48-, 96-, 384-, 1536-well
plastic or glass plates
Microscope slide compatibility X X
Computer workstation X X
MetaXpress image acquisition
and analysis software
X X
MDCStore integrated database X X
AcuityXpress cellular
informatics software
option option

1 Not compatible with transmitted light
2 Not compatible with liquid handling