2006 Automated Electrophysiology Users Meeting
Thanks to everyone who attended our Automated Electrophysiology Users Meeting in Salt Lake City. We also
thank all of our presenters, especially our distinguished keynote speaker, Dr. Michael Sanguinetti, Ph.D.,
Department of Physiology, University of Utah.
The presentation topics are listed below and most are available for download in PDF format. If a presentation
is not available here, please contact the author directly.
Keynote Presentation
- hERG Channel Block: The Bane of Drug Discovery
Dr. Michael Sanguinetti, Ph.D., Professor, University of Utah
Safety Applications
- Cardiac safety testing with the PatchXpress
Dr. Nathan Lautermilch, Ph.D., MDS Pharma
- QT risk assessment and the role of PatchXpress: An industry perspective
Dr. Ruth Martin, Ph.D., Abbott Laboratories
Pharma Drug Discovery Applications
- Population patch-clamp: an enabling technology for the discovery of potassium channel openers
Dr. Claire Townsend, Ph.D., Investigator, GlaxoSmithKline
- Optimization of automated EP assays: case studies with calcium and potassium channels
Dr. Owen McManus, Ph.D., Senior Investigator, Merck Research Laboratories
- Integrating high throughput electrophysiology into the drug discovery process
Dr. Peter Haddock, Ph.D., Senior Principal Scientist, CNS Biology, Pfizer, Inc.
Biotech Drug Discovery Applications
- Using the OpusXpress as a Secondary Screening Platform in the Senomyx Discovery Process
Dr. Bryan Moyer, Ph.D., Senior Scientist, Senomyx, Inc.
- Embedded Reporters: Ion channels and GPCRs
Dr. Stephen Smith, Ph.D., Senior Scientist, Lexicon Genetics
- Compound Evaluation on Na+ Channel Isoforms using the OpusXpress 6000A system
Dr. George Ehring, Ph.D., Allergan
- A year with IonWorks Quattro—advantages, challenges and lessons learned
Dr. Andrew Southan, Ph.D., Head of Ion Channel Pharmacology, BioFocus
Molecular Devices Corporation Breakouts
- PatchXpress Update
David Yamane, Director of Marketing
- IonWorks Update
Shawn Handran, Ph.D., Product Marketing Manager
- DataXpress 2: Taking Patch Clamp Analysis to the Next Level
Jan Dolzer, Ph.D., Product Marketing Manager
Poster Presentations
- Evaluating The Utility Of The IonWorks Quattro in a Drug Discovery Setting
Shannon Zellmer, David Printzenhoff, Douglas Krafte, Neil Castle Icagen Inc, 4222 Emperor Boulevard, Durham, NC 27703
- The Development of Cardiac Ion Channel Screening Assays for Safety Profiling of Compounds Early in the Drug Discovery Process
Ray Helliwell, Louise Webdale, Helen Swain, Ed Maughfling, Jonathan Mann, Duncan Jarman and Umesh A. Patel., Cytomyx Ltd.
- De-risking the cardiotoxic effects of pharmaceutical compounds with in vitro hERG and ex vivo Langendorff heart assays
Liang Guo, Heather Guthrie and Kristy Bruse, Hoffmann-La Roche Inc.
- Cardiac Ion Channel Applications of PatchXpress Automated Electrophysiology
Yuri A. Kuryshev, Jessica Brimecombe, Glenn E. Kirsch, and Arthur M. Brown, ChanTest, Inc.
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