2005 Automated Electrophysiology Users Meeting

The Automated Electrophysiology Users Meeting in Long Beach, California was a huge success, thanks to all of our presenters and participants! The presentation topics are listed below. The downloadable presentations are in PDF format.

Some presenters were not able to provide a PDF of their presentations. Please contact presenters directly for more presentation information.

• Meeting Agenda
  • Download agenda  [PDF]
• Keynote address
  • The impact of automated electrophysiology on ion channel drug discovery and academic research in the 21st century, Professor Henry Lester, California Institute of Technology
• Using IonWorks HT and PatchXpress systems in the same lab
  • Use of automated electrophysiology platforms for compound profiling at hERG K⁺ channels  [PDF], Peter Miu, Amgen (PatchXpress, IonWorks HT, IonWorks Quattro)
• PatchXpress session
  • How to get the best IC₅₀s  [PDF], Jan Dolzer, Molecular Devices (PatchXpress)
  • Rapid ICE (Rapid Ion Channel Electrophysiology): an ion channel screening service using the PatchXpress 7000A system  [PDF], Claire Quinn, Ph.D., Quintiles, Ltd. (PatchXpress)
• IonWorks HT session
  • hERG safety assay-integration into a high throughput ADME screening facility  [PDF], Jayne Ford, Cyprotex (IonWorks HT)
  • Positioning of IonWorks HT in ion channel drug discovery  [PDF], Del Trezise, GSK (IonWorks HT)
  • Compound screening against cardiac sodium channels with IonWorks™ HT using a native cell line  [PDF], Qiang Lu, Wyeth (IonWorks HT)
• OpusXpress session
  • Using the OpusXpress to investigate ligand-gated ion channels and transporters in an academic laboratory  [PDF], Daryl Davies, Ph.D., University of Southern California (OpusXpress)
  • Structure-function analysis of hERG pharmacology using unnatural amino acid mutagenesis  [PDF], Paul Bennett, Neurion Pharmaceuticals (OpusXpress)

• Molecular Devices product update and DataXpress tutorial session

  • IonWorks Quattro™ system with Population Patchclamp™ technology  [PDF], Shawn Handran, Molecular Devices
  • DataXpress 2.0 Overview  [PDF], Jim Rountree, Molecular Devices (DataXpress)