Monday, September 22 - 11:55 am-12:40 pm, Room A109
Automated methods for predicting intestinal absorption in ADME and pre-ADME applications David Wexler, AGY Therapeutics. Sponsored by Millipore.
Monday, September 22 - 12:50 pm-1:30 pm, Room A105
IMAP® - a technology grows up Annegret Boge, Molecular Devices Corporation
Tuesday, September 23 - 12:50 pm-1:30 pm, Room B110
Discovery-1™: predefined protocol for high content screening Christopher Maki, Molecular Devices Corporation
Wedenesday, September 24 - 12:50 pm-1:30 pm, Room A109
IonWorks™ automated high throughput patch clamp electrophysiology for drug discovery Wilhelm Lachnit, Ph.D., Molecular Devices Corporation
Oxidative burst: Amplex Red detection of hydrogen peroxide release from activated human neutrophils and cell lines using FlexStation™ II384 microplate reader Abstract ID: 030530111841 Authors: Carole Crittenden*, Anna Christiensen, Molecular Devices Corp; Elisabeth Gardiner, Kalypsis
Screening compounds that modulate ionic currents using the IonWorks™ HT system Abstract ID: 030401104006 Authors: James Costantin, Andrew Wittel, and Wilhelm Lachnit, Molecular Devices Corporation
Expansion of IMAP® application: ATP tolerance and use of substrates with a high propoprtion of acidic residues Abstract ID: 030530120027 Authors: Annegret Boge, Liz Gaudet, Luke Lavis and Richard Sprotsman, Molecular Devices Corporation
Adaptation of a high sensitivity 384-well solid phase assay platform to 1536 wells: CatchPoint™ for cyclic nucleotides and tyrosine kinase activity Abstract ID: 030530122619 Authors: Annegret Boge, Jonathan Petersen, Jeannie Nguyen, Gayle Teixeira and Richard Sportsman, Molecular Devices Corporation
NEW! SpectraMax® M2
See the new dual-monochromator,multi-detection microplate reader with a dual-mode cuvette port and 6- to 384-well microplate reading capability. Detection modalities include absorbance and fluorescence intensity with optical performance comparable to a top-of-the-line dedicated spectrofluorometer or spectrophotometer.
FlexStation™ II384
View our newest fluorometer with integrated fluid handling offers the highest level of flexibility in developing functional cellular assays and analyzing real time kinetic data such as intracellular calcium, membrane potential and oxidative burst assays.
AquaMax™ DW4 liquid handler
The AquaMax™ DW4 Liquid Handler provides precise dispensing and thorough washing all in one instrument. This combination dispenser and washer will handle 96- through 1536-well plate formats. The dispensing volume goes down to 0.5 µL and is ideal for low volume dispensing into 384-well microplates. The unique design offers a manifold to handle up to 4 separate solutions with no priming between fluids, stirring capability to keep fluid in suspension, and small footprint with internal vacuum and pressure pumps.
IMAP® assay technology for kinase and phosphatase activity
Understand how IMAP can monitor kinases spanning the entire human kinome regardless of substrate acidity or ATP requirements. Two new prevalidated kits, Abl and IKKb, join seventeen other kits demonstrating the versatility of our screening system that eliminates the need for radioactivity and antibodies.
Discovery-1™
Look into how our automated high content screening system simplifies assays for neurite outgrowth, angiogenesis, molecular translocation, apoptosis, proliferation and receptor internalization with new predefined protocols.
IonWorks™ HT
See our high-throughput, automated electrophysiological screening system. IonWorks can perform functional ion channel assays for lead optimization, pharmacology or hERG safety profiling of 200+ compounds/day or up to 3,000 patched cells per day!
Analyst® GT Multimode Reader
Our Analyst platform has been redesigned to dramatically improve read speed, precision, and cross-talk in 96-, 384-, and 1536-well plates in all five assay modes. In addition to numerous hardware upgrades, the software has evolved to contain many features that our Analyst and Acquest users have requested.
