2001 MDC 5th International Drug Discovery Conf.
This year's International Drug Discovery Conference was a huge success, thanks to all of our presenters! The
presentation topics are listed below. For those presentations having a downloadable (pdf) version, we have indicated
the file size of the pdf.
characterization of receptors
- Orphan GPCR functional genomics: trials and tribulations of assay development
Dr. Robert S. Ames, GlaxoSmithKline
Download presentation [PDF] (872 K)
- Identification and characterization of a novel Gi linked receptor for ADP
Dr. Frederick J. Monsma, Jr., Schering-Plough Research Institute
Download presentation [PDF] (660 K)
- Use of the FLIPR in the study of the GABAb heterodimeric receptor
Dr. Martyn D. Wood, GlaxoSmithKline
Download presentation [PDF] (1.2 MB)
- High receptor reserve and GPCR cross talking in a mGluR2 FLIPR assay
Dr. Michael P. Johnson, Lilly Research Laboratories
Download presentation [PDF] (236 K)
- Deorphanization of human 7TM receptors using FLIPR success stories, pitfalls and potential solutions
Dr. Philip G. Szekeres, GlaxoSmithKline
Download presentation [PDF] (2 MB)
assay development and scale-up
- FlexStation: A new approach for functional cell analysis
Dr. Jeff Jerman, GlaxoSmithKline
Download presentation [PDF] (1.1 MB)
- A comparison of P2Y receptor-mediated changes in intracellular Ca++ vs. membrane potential
Julie Brothers, Roche Bioscience
Download presentation [PDF] (228 K)
- Development of an engineered receptor to study tissue-specific Gq signaling
Dr. Alexander C. Zambon, Gladstone Institutes of Cardiovascular Disease
Download presentation [PDF] (1.3 MB)
- Evaluation of the ScreenStation for 864- and 1536-well assays
Jennifer D. Irvine, Affymax Research Institute
other assays (ion channel and SPA)
- A bead-based scintillation proximity assay: A comparison between the CLIPR and the MicroBeta
Joy Prisco, Sphinx Laboratories
Download presentation [PDF] (1.7 MB)
- Screening with MDC's membrane potential kit
Dr. Edward Kaftan, R.W. Johnson Pharmaceutical Research Institute
Download presentation [PDF] (204 K)
- Functional assay of transporters using a voltage sensitive dye in combination with FLIPR
Dr. John Dunlop, Wyeth Neuroscience
- Evaluation of FLIPR membrane potential dye for studying K+ channels in smooth muscle
Kristi Lynn Whiteaker, Abbott Laboratories
Download presentation [PDF] (320 K)
alternative reporter mechanisms
- Assay optimization for screening PKC with fluorescence polarization
Dr. Martin Zoche, Byk Gulden
Download presentation [PDF] (320 K)
- Validation of GPCR functional assays in a novel system with promiscuous G proteins
Dr. Matthew H. Hsu, Neurocrine Biosciences
- Development of a fluorescent polarization assay in FLIPR
Mark Wolfe, Pharmacia
- Affinity measurements of small molecules for cell bound and purified receptors
Dr. Susan M. Keating, Genentech, Inc.
- Real experiences using fluorescence polarization for high-throughput screening
Dr. Mohammed A. Kashem, Boehringer Ingelheim Pharmaceuticals, Inc.
Download presentation [PDF] (1.1 MB)
- IMAP: A new technology for uHTS of phosphodiesterases, phosphatases, and kinases
Dr. Wei Huang, Molecular Devices
Download presentation [PDF] (348 K)
- Mitochondrial diseases: Strategies for therapeutic development derived from a novel FLIPR assay for membrane potential
Dr. James A. Dykens, MitoKor
automation and integration
- ELISAs for HTS
Dr. Richard Sportsman, Molecular Devices
Download presentation [PDF] (220 K)
- Overview of Analyst and Acquest integration: update on Active X controls
Michael Biros, Molecular Devices
Download presentation [PDF] (1.5 MB)
- Selectivity testing of compounds against protein kinases — KinaseProfiler™
Dr. Sue Dale, Upstate Discovery Ltd.
Download presentation [PDF] (144 K)
posters
|
