Application Notes
Please select from among the application categories below.
| Microplate Imaging | Threshold Contaminant Detection |
- PatchXpress Product Update
- IonWorks Product Update
- Kv1.5 Potassium Channel Assay Using the IonWorks HT System
- hERG Safety Screening Assay Using the IonWorks HT System
- Nav1.5 Sodium Channel Assay Using the IonWorks HT System
- Rapid Hit Confirmation and Early hERG Liability Testing Using the IonWorks HT System
- Optimal Assay Conditions for hERG Pharmacology Studies
- Parallel Resistance Calculator for IonWorks Quattro Seal Resistance Distributions and the Transfer of Assays From Single-hole to Population Patchplate Substrates
- IonWorks Software Version 2 Broadens the Experimental Repertoire of the IonWorks HT and IonWorks Quattro Systems
- Primary Screen of a Directed Compound Library Against Nav1.5 Channels Using Population Patch Clamp Technology
- Conducting ligand-gated ion channel (LGIC) studies on the PatchXpress 7000A system
- Recording of Icrac in RBL-1 cells on the PatchXpress 7000A Automated Patch Clamp System
- Validation of a multiple compound addition assay for hERG ion channel on the IonWorks Barracuda System
- Synchronizing electrophysiology and imaging studies with Axon pCLAMP and MetaMorph Software
- FLIPR Calcium 3 Assay Kit: An Optimal No-Wash Fluorescence Calcium Indicator Reagent for Non-Optimal Calcium Responses
- FLIPR Membrane Potential Red and Blue Assay Kits on FLIPR Tetra Instrument: NaV1.5 Sodium Channel Modulation Assay Optimization
- FLIPR Tetra and Voltage Sensor Probes: Ratiometric Determination of Barium Chloride-Induced Changes in Inward Rectifying Potassium Channels (Kir) in Rat Basophilic Leukemia Cells
- FLIPR Tetra Fluorometric Imaging Plate Reader and FLIPR Calcium Assay Kit: Comparison of Intracellular Calcium Measurements in 96-, 384- and 1536-Well Formats
- Adherent CHO Mito-Photina/H3 Photoprotein Cell Assays Performed on the FLIPR Tetra System with Aequorin Option
- Measuring Intracellular Calcium with the FLIPR I and FLIPR 384 Fluorometric Imaging Plate Reader Systems
- Measuring Intracellular Calcium with the FLIPR Calcium Assay Kit on Fluorometric Imaging Plate Reader Systems
- Comparison of the Ca2+-Sensitive Dyes Fluo-3 and Fluo-4 Used with the FLIPR Fluorometric Imaging Plate Reader Systems
- Using the FLIPR System and the FLIPR Calcium Assay Kit to Develop a High-Throughput HEK293/GPCR "X" Assay
- Measuring Membrane Potential Using the FLIPR Membrane Potential Assay Kit on FLIPR Systems
- Measuring Membrane Potential Using the DiBAC with the FLIPR I and FLIPR 384 Fluoremetric Imaging Plate Reader Systems
- Monitoring of Mitochondrial Membrane Polarization Change in Live Cells Using JC-1Dye
- Measuring Intracellular pH with the FLIPR I and FLIPR 384 Fluorometric Imaging Plate Reader Systems
- High througphut cardiotoxicity assays using stem cell-derived cardiomyocytes
- Measuring GPCR Activity Using the Tango GPCR Assay on the FLIPR Tetra Fluorimetric Imaging Plate Reader
- FLIPR Calcium 5 Assay Kit: A homogeneous solution for GPCR assays
-
Enhance your calcium screens with FLIPR Calcium 6 Assay Kits (Application Highlight)
- Angiogenesis drug discovery: automating tube formation assays with the Discovery-1 system
- High-content analysis of the various stages of apoptosis with the MetaXpress Cell Health Application Module
- Assaying Cardiotoxicity with ImageXpress High Content Screening Systems
- Homogeneous Cytotoxicity Assay
- Homogeneous High-Throughput Live Cell GPCR Binding Assay
- High Throughput Anchorage-Independent Cell Colony Assay
- High Throughput Fluorescence Focus Assay for Live Virus-Based Vaccine Development
- High Throughput RNAi Screen for DNA Damage
- Homogeneous High-Throughput Cell Surface Binding Assay for Antibody Discovery
- High-Throughput Imaging of Zebrafish Embryos for Drug Discovery
- High-Throughput Cell Migration Assay
- Total and Phospho-Protein Detection
- Cell Clonality Screening for Hybridoma Technology
- High Throughput Arrayed NF-κB Transcription Factor Profiling
- Fluorescence and Laser Scatter Imaging of Mouse Embryonic Stem Cells and Embryoid Bodies
- High-Throughput Two-Color Mitotic Index Assay
- ImageXpress Velos System - HTS: Automated Plate Handling for Walk-away Functionality
- High-Content Screening of GPCR Activation Using MetaXpress, AcuityXpress Software and the Transfluor Assay System
- Homogeneous Antibody Binding Assay for High-Throughput Screening
- Assaying cardiotoxicity with ImageXpress High Content Screening Systems
- Neuronal Stem cells on ImageXpress Micro
- Live cell kinetics assay utilizing the ImageXpress Micro System
- High-content screening of neuronal toxicity using iPSC-derived human neurons
- Multiplexed High Content Hepatotoxicity Assays using iPSC-derived Hepatocytes (Application Highlight)
- CellKey System Application Highlight 9 - Endogenous Receptor Evaluations: Gi- and Gs- Coupled GPCR Receptor Subtyping and Schild Analysis
- CellKey System Application Highlight 10 - Analyzing Endogenous Gi- and Gs- Coupled GPCRs in Non-Adherent Cells with the CellKey System
- Receptor Panning
- Identifying the G-Protein Coupling Mechanism of GPCRs
- Deconvolution of Signal Transduction Pathways
- Endogenous Receptor Evaluations: Receptor Subtyping and Schild Analysis
- Analyzing Endogenous Receptors in Non-Adherent Cell Lines and Primary Cells with the CellKey Small Sample 96W Microplate
- Monitoring Functional Inhibition of a Cell Surface Receptor using RNA Interference
- Label-free Primary Screening of Endogenous Targets
- Label-free Analysis of Primary Cells
- Assessing Slide Flatness
- Biological Relevance of GenePix Results
- GenePix 4000B PMT Adjustment
- GenePix 4000B SNR and PMT Gain Setting
- GenePix 4100A Choosing Emission Filters
- Guide to Microarray Analysis
- Making GenePix Array List (GAL) Files
- Scripting in GenePix Pro
- Assessing Fluorescent Microarray Imaging Systems
- Using the GenePix 4400A Microarray Scanner
to generate high-resolution images of CGH
2.1M feature arrays
- Monitoring Receptor Mediated Changes In[Ca2+]i Using Single- and Dual-Wavelength Indicators on the FlexStation Benchtop Multi-Mode Microplate Reader
- Optimized Wavelength Scanning of Fluorescent Proteins with the SpectraMax Paradigm Platform and TUNE Technology
- OxiSelect ORAC Assay on Molecular Devices' Fluorescence Microplate Readers
- AlphaLISA Screen on the SpectraMax Paradigm Multi-Mode Microplate Detection Platform
- Measurement of Proteasome Inhibition in Live Cells in Molecular Devies Microplate Fluorometers
- Nimbus Transil Early ADME on SpectraMax Microplate Readers
- Multiplexing Fluorescent and Chemiluminescent Live Cell Reporters to Dissect NFκB Signal
- High-Throughput Melamine Detection with SpectraMax Absorbance Microplate Readers and Abraxis' Melamine
- High-Throughput Melamine Detection with SpectraMax Absorbance Microplate Readers and Romer Labs'
- Automated Turnkey Solubility and Permeability Assays
- Fluorescence-based Measurement of Endothelial Cell Migration Through Collagen Using the BD Falcon FluoroBlok Insert System
- Measuring Cell Proliferation with SpectraMax M5, M2 and Gemini Microplate Readers Using the CyQUANT Cell Proliferation Assay
- Dual-glo Luciferase Reporter-gene Assay on the SpectraMax M5, LMax II 384 and Analyst GT Microplate Readers
- HTRF cAMP Dynamic 2 and IP-One Assays Using the SpectraMax M5e Multi-detection Microplate Reader
- Detection Limit and Linear Range of Ready-to-glow Secreted Metridia Luciferase Determined on the SpectraMax L Luminometer
- Chemiluminescent VEGF ELISA Using the SpectraMax L Microplate Luminometer
- Using Promega's CellTiter-Glo Luminescent Cell Viability Assay with SpectraMax L and SpectraMax M5 Microplate Readers
- Measurement of Residual Sugar in Wine Using the SpectraMax Plus384 Microplate Reader
- Measurement of Phenolic Compounds in Red Wines Using the SpectraMax Plus384 Microplate Reader
- Measurement of L-Malic Acid in Wines Using the SpectraMax Plus384 Microplate Reader
- High-Throughput Melamine Detection with SpectraMax Absorbance Micrplate Readers and Beacon Analytical Systems' Melamine Plate Kit
- MycoAlert Mycoplasma Detection Assay (Lonza) on the SpectraMax L Microplate Luminometer
- Quantitating Double-stranded DNA with Quant-iT PicoGreen dsDNA Reagent and SpectraMax Fluorescence Microplate Readers
- IMAP FP Kinase Assasy on the SpectraMax M5 Multi-Mode Microplate Reader
- ß-Lactamase-Inhibitor Protein Binding Affinities: Detection of Hydrolysis of ß-Lactam Substrate by TEM-1 Enzyme and Inhibitor Binding Using the FlexStation 3 Microplate Reader
- Comparison of Photina Luminescent Calcium Mobilization Assays on both the FlexStation 3 and FLIPR Tetra Systems
- Gq-coupled Receptor Assays Using the FlexStation System: M1 Muscarinic Receptor
- Gq-coupled Receptor Assays: A Comparison of FlexStation and FLIPR Systems
- Stem Cell-derived Human Neurons in CNS Drug Discovery
- HiTest Liquid Handling Systems Quickly and Easily with the PathCheck Sensor
- The PathCheck Sensor: a Powerful New Tool for Microplate Analysis
- Verify Small-volume Dispenser Performance with the Award-winning PathCheck Sensor
- Eliminate Temperature Errors in Pathlength Measurements Using PathCheck Sensor
- Measure DNA and RNA Quickly and Easily in SpectraMax Microplate Spectrophotometers
- Using the NanoOrange Protein Kit in the Gemini XS, Gemini EM and SpectraMax M2 Microplate Readers
- MTT Reduction - A Tetrazolium-based Colorimetric Assay for Cell Survival and Proliferation
- A Microtiter-based Assay for the Determination of ID50S of ß-lactamase Inhibitors employing reporter Substrates Detected at UV or Visible Wavelengths
- Using the OliGreen Oligonucleotide Quantitation Reagent in the Gemini XS, Gemini EM and SpectraMax M2 Microplate Readers
- Using the NanoOrange Protein Kit in the Gemini XS, Gemini Em and SpectraMax M2 Microplate Readers
- Microdetermination of Phosphorus Using the SpectraMax Plus Microplate Spectrophotometer: Choice of Microplate, Cuvette, or Test Tube Assay Formats
- Making Optical Density Measurements Automatically Corrected to 1cm Pathlength in the SpectraMax Plus Microplate Spectrophotometer
- PathCheck Applied to Measurement of Protein Solutions inthe SpectraMax Plus Microplate Spectrophotometer
- Verifying Multichannel Pipettor Performance with Standard Dispense Solutions in the SpectraMax Plus
- Selecting Excitation and Emission Wavelengths Using the SpectraMax Gemini Microplate Spectrofluorometer - Basic Principles
- Optimaizing Excitation and Emission Wavelengths for Narrow Stokes' Shift Fluorophores Using the SpectraMax Gemini and SoftMax Pro
- DNA and RNA Measurements in SpectraMax Microplate Spectrophotometers
- Fluorometric Protease Assays in the SpectraMax Gemini Microplate Spectrofluorometer: Example Using Caspase-3
- Measurements of Molecular Beacons in the SpectraMax Gemini Spectrofluorometer
- Dual-luciferase Quantitation in the Lmax Microplate Luminometer
- ATP Quantitation in the Lmax Microplate Luminometer
- Ca++-Induced G Protein-coupled Receptor (GPCR) Activation Monitored via Aequorin Luminescence in the Lmax Microplate Luminometer
- LIVE/DEAD Viability/Cytotoxicity Assay for Animal Cells Using the SpectraMax Gemini XS Fluorescence Microplate Reader
- Measurement of Green Fluorescent Protein in the SpectraMax Gemini XS Spectrofluorometer
- Sensitivity Test for Molecular Devices Microplate Fluorometers
- A Stable, Sensitive Fluorescence-based Method for Measuring Cyclic AMP Using the SpectraMax Gemini XS Spectrofluorometer
- A Stable, Sensitive Fluorescence-based Method for Measuring Cyclic GMP
- Fluorescence-based Mitochondrial Function Analysis
- LA372 SYTOX Kinetic Studies
- Microplate-Based Endotoxin Testing in GLP/GMP Environments with the VersaMax Absorbance Microplate Reader and Pyrochrome Assay
- Noninvasive Measurement of Fluorescent Proteins in Live Cells in Molecular Devices Microplate Fluorometers
- Cytotoxicity in Cells: Easy Determination Using Lonza ViaLight Plus and ToxiLight BioAssays on the SpectraMax L Microplate Luminometer
- Faster Chemiluminescent cAMP Detection by HitHunter cAMP XS+ on the SpectraMax L Luminescence Microplate Reader
- Optimized Settings to Validate the Molecular Devices Analyst GT/HT Microplate Readers with the Transcreener Fluorescence Intensity Assays (BellBrook Labs)
- Optimized Settings to Validate the Molecular Devices Analyst GT/HT Microplate Readers with the Transcreener TR-FRET Assays (BellBrook Labs)
- Optimized Settings to Validate the Molecular Devices Analyst GT/HT Microplate Readers with the Transcreener Fluorescence Polarization Assays (BellBrook Labs)
- Optimized Settings to Validate the Molecular Devices Gemini XPS/EM Microplate Readers with the Transcreener Fluorescence Intensity Assays (BellBrook Labs)
- Optimized Settings to Validate the Molecular Devices SpectraMax M2 Microplate Readers with the Transcreener Fluorescence Intensity Assays (BellBrook Labs)
- Optimized Settings to Validate the Molecular Devices SpectraMax M5/M53/FlexStation Microplate Readers with the Transcreener Fluorescence Intensity Assays (BellBrook Labs)
- Optimized Settings to Validate the Molecular Devices SpectraMax M5 Microplate Readers with the Transcreener TR-FRET Assays (BellBrook Labs)
- Optimization of a muscarinic M3-receptor assay using frozen "Assay Ready" CHO cells on the FlexStation 3 System: The impact of calcium dye selection and cell culture conditions
- Maximizing cell wash performance with AquaMax 2000/4000 Microplate Washers and cell wash heads
- Fluorescence-based quantitation of small DNA samples with the SpectraDrop Micro-Volume Microplate
- Maximizing performance of the SpectraDrop Micro-Volume Microplate for DNA quantitation
- Fluorescent ADP detection with the ADP Quest Assay on the SpectraMax Gemini EM Fluorescence Microplate Reader
- Washing MAGPIX beads with AquaMax Washer
- Optimizing SpectraMax Paradigm Settings for use with Transcreener FP
- Toxicity assays using induced pluripotent stem cell-derived cells
- Measuring marker expression with imaging cytometry on a plate reader
- A Phenol-free DNA Extraction Method
- Applications of Rapid Immunoassays (FAST ILA) in Cell Culture/fermentation and Process Development Using the Threshold System
- Contaminant Bovine IgG Assay
- Contaminant Bovine Transferrin Assay
- Contaminant BSA Assay
- Contaminant Host Cell-derived Protein Assay
- Contaminant Human Transferrin Assay
- DNAse Qualification and Sample Treatment
- Escherichia coli Plasmid Copy Number Assay
- Optimizing the Labeling of Proteins
- Preparation and Qualification of DNA stand for Threshold Total DNA assay
- Protein A Contaminant Assay
- Protein G Contaminant Assay
- Quantitation of residual DNA in Final Product
- Sequence-Specific DNA Assay
- Nimbus Transil Early ADME on SpectraMax Microplate Readers
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Affordable multi-mode detection and PathCheck Technology with the new SpectraMax M3 & M4 Microplate Readers. Learn more.
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