- No Need to Manually Scan Your Slides. Use the multiplexed image acquisition with your predefined settings and you do not need to manually scan each individual array anymore. Select multiple scan areas on one microarray and set your scan parameters for independent scans and click on Data Scan All. A GenePix® Microarray Scanner controlled by GenePix® Pro 7 Acquisition and Analysis Software will do the image acquisition and save the images to your desired location.
- Manual Gridding No Longer Necessary. Rely on the powerful spot finding algorithms. Analyze any microarray TIFF image from any scanner, including hexagonally packed arrays, using a set of proprietary spot-finding algorithms in GenePix® Pro 7 Acquisition and Analysis Software. Global alignment algorithms determine translation, rotation and skew of blocks with features. In addition to finding circular or square features, the software has an edge-detection option for segmenting irregularly shaped features from background.
- Define Your Own Flags. Define your own flag with the automated feature flagging. The User-Defined Flag Features interface allows you to design and save multiple-parameter Boolean queries for automated feature flagging. Queries can easily be shared between collaborators to help standardize quality control practices within a group of users.
- Choose the Best Background Subtraction Method. With each microarray experiment, it is critical to calculate the best-possible numerical representation of biological changes on the array, which is often hampered by substandard array quality. GenePix® Pro 7 Software allows you to choose between several background subtraction methods: local, global, morphological or negative control methods. Or, where appropriate, choose to have no background subtraction at all.
- Unattended Batch Analysis. GenePix® Pro 7 Acquisition and Analysis Software simplifies batch analysis. Simply load a group of TIFF images to the Batch Analysis Tab, assign layout files and press Start. GenePix® Pro 7 Acquisition and Analysis Software will automatically run spot-finding algorithms, extract numerical values, flag features and save a results file for each image. With the Browse Tool, users can quickly review results of the completed batch.
High Resolution Scanning Specifications
Recommended for 4400/4300 Microarray Scanners and SL50 Automated Slide Loader
Processor: IBM-compatible computer with an Intel "Quad Core" processor 2.9 GHz
Operating System: Windows 7 Ultimate, 64-bit, english
Memory: 8 GB RAM or more
Storage: 1 TB hard drive (for image storage)
Graphics: 1 GB video card
Display: 22 inch, 1680 x 1050, 16M colors
Other Features: 16x DVD-ROM
Connectivity: 3 USB ports (one for the USB software protection key*, one for the scanner, and one for the slide loader) or network connection, Internet Explorer 7
Standard Specifications
Recommended for GenePix 4000B and 4100 USB Microarray Scanners.
Processor: IBM-compatible computer with an Intel Pentium "Dual Core" processor 1.6 GHz or faster
Operating system: Windows XP or Vista 32-bit edition operating system
Memory: 4GB RAM
Storage: 160 GB hard drive (for image storage)
Graphics: Integrated Video Card
Display: 1280 x 1024 display
Other Features: Optical drive with CD read and write capabilities (CD-RW)
Connectivity: At least 2 free USB port or network connections (one for the USB software protection key*, and one for the scanner)
Internet Explorer 6.0 or higher
Minimum Specifications
Recommended for SCSI Microarray Scanners.
Processor: IBM-compatible computer with an Intel "Dual Core" processor 1.6 GHz or faster
Operating system: Operating system: Windows XP (32 Bit)
Memory: 4GB RAM
Storage: 160 GB hard drive (for image storage)
Graphics: Integrated Video Card
Display: 1280 x 1024
Other Features: Optical drive with CD read and write capabilities (CD-RW)
Connectivity: At least 2 free USB port or network connections (one for the USB software protection key, and one for the scanner)
One available PCI interface for SCSI card
Internet Explorer 6.0 or higher
Microarray Systems:
Microarray Software:
Genomics: Directed at the genome sequence itself, microarrays have been used to identify novel genes, binding sites of transcription factors, changes in DNA copy number, and variations from a baseline sequence, such as in emerging strains of pathogens or complex mutations in disease-causing human genes.
- SNP genotyping arrays
- Arrayed comparative genomic hybridization (aCGH) arrays
Transcriptomics: The use of high-density microarrays has impacted the measurement of transcript levels to study complex diseases. With the latest development of microarray technology, it is now possible to quantify transcript levels globally and to integrate such data with information relating to disease. Microarrays based transcriptomics enables mapping a critical genomic region for a disease using affected and unaffected individuals and then pinpointing the responsible gene by identifying differentially expressed genes in the critical region.
- Gene expression arrays
- RNA interference (RNAi) arrays
- MicroRNA (miRNA) arrays
Proteomics: Although the analysis of the full proteome has not yet been achieved, rapid progress is being made with microarrays in the field of proteomics. Proteomes exhibit large and dynamic complexity; the number for distinct proteins in mammals will certainly exceed the number of genes, requiring the right technology to be in place for the analysis. The flexibility of the GenePix Microarray Scanner system, and especially the high-throughput capabilities of the GenePix SL50 Automated, provides adequate tools to researchers.
- Protein arrays
- Peptide arrays
- Antibody arrays
- ELISA arrays
- Reverse Phase Arrays
Epigenomics: The gene carries the basic unit of information, but this information has an impact only once it is properly programmed by the epigenome. The DNA methylation pattern is cell type specific and correlates with chromatin structure. DNA microarrays are being utilized to identify methylation patterns, and the GenePix Microarray Scanner automation solution allows the researcher to identify these patterns faster.
- DNA methylation arrays
- Chromatin immunoprecipitation (ChIP) arrays
Novel Applications: The creativity and broad applicability of microarray-based research has no limits and is demonstrated by the vast variety of different microarray applications to conduct large-scale quantitative analysis. With the GenePix® Microarray Scanner System you have the most flexible solution and freedom in your research.
- Tissue arrays
- Quantum Dots
- Carbohydrate Arrays
- Chemical Compound Arrays
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GENEPIX PRO V.7 LICENSE |