SpectraTest LM1 Luminescence Validation Plate
A comprehensive tool for verifying Molecular Devices’ Microplate Readers are performing to manufacturing specifications.
Microplate readers from Molecular Devices are built to generate quality measurements over extended use. Backing up the robustness of the systems is the SpectraTest® LM1 Luminescence Validation Plate, a valuable tool for all users to verify their luminescence-capable microplate readers are operating correctly, and an essential tool for GLP and GMP laboratories, where regularly documenting instrument performance is a must.
Comprised of 9 distinct test areas, the SpectraTest LM1 Validation Plate checks reader performance to the same specifications as the instruments were built to, ensuring that the luminescence readings are as accurate and precise as the day your microplate reader first arrived. The 13 individual tests performed by the SpectraTest LM1 Validation Plate provide superior coverage to validation plates offered for other luminescence systems on the market. Unique to the plate also is an assessment of the lower limit of detection (LLD), confirming the sensitivity of the luminescence-capable readers.
Pre-formatted SoftMax® Pro Data Acquisition & Analysis Software protocols are used to automatically generate and analyze the data, reporting failures as out of specification. Additional 21 CFR Part 11 compliance tools are available through SoftMax® Pro GxP Compliance Software for controlled access to the test results and an audit trail of activities.
Qualification of a microplate reader is limited only by the tools available, and the more comprehensive nature of the SpectraTest Validation Plate family has established a legacy of trust in the IQOQ of microplate readers from Molecular Devices.
9 Test Areas for Increased Luminescence Measurement Confidence
- Background noise to sample the measurement noise of the system. This includes separate tests for background noise and spikes.
- Lower limit of detection (LLD) to estimate the minimum measurable signal of the microplate reader
- Crosstalk to measure the light from adjacent wells.
- Left-to-right bias to check for significant differences in measuring capability at from the left edge of the plate to the right edge.
- Linearity to verify the linearity of the luminescence signal detected.
- Kinetic noise (Low Signal) to measure the stability of the optical system at low signals. This includes separate test for kinetic noise, spikes, and drift at low signal.
- Kinetic noise (High Signal) to measure the stability of the optical system at high signal. This includes separate tests for kinetic noise and drift at high signal.
- Top-to-bottom bias to check for significant differences in measuring capability from the top edge of a microplate compared to the bottom edge.
- Well-to-well precision to assess measurement reproducibility across the plate.