Microplate Readers

Multi-Mode Microplate Reader Comparison Table

Features

SpectraMax

 

F3 Multi-Mode Microplate Reader
 F5

F5 Multi-Mode Microplate Reader
F3

SpectraMax Paradigm Multi-Mode Detection Platform

Paradigm
SpectraMax i3 Multi-Mode Microplate Detection Platform

i3
FlexStation 3 Benchtop Microplate Reader
Flex-
Station 3

SpectraMax M5e Multi-Mode Microplate Reader (with HTRF capabilities)
M5e

SpectraMax M5 Multi-Mode Microplate Reader
M5

SpectraMax M4 Multi-Mode Microplate Reader
M4

SpectraMax M3 Multi-Mode Microplate Reader
M3

SpectraMax M2 Multi-Mode Microplate Reader
M2e

SpectraMax M2e Multi-Mode Microplate Reader (top and botom read for cell-based assays)
M2

Absorbance

x

x

x

x

x

x

x

x

x

 x

Fluorescence

x

x

x

x

x

x

x

x

x

x

x

Luminescence

x

x

x

x

x

x

x

x*

x*

 x

x

Time-Resolved
Fluorescence (TRF)

x

x

x

x

x

x

 

x*

x*

x

 

HTRF Certified

x

x

x

x

 

 

 

 

 

 

 

Fluorescence Polarization

x

x

x

x

x

 

 

 

 

x

 

AlphaScreen/
AlphaLisa

x

x










Western Blot Detection x x

User-Upgradeable Application Cartridges 

x

x










Imaging Cytometer option


x










Wavelength
Range (nm)

230 - 1000

FL
250-850
Abs
230-1000

FL 250-850,
Abs 200-1000

FL 250-850,
Abs 200-1000

FL 250-850 ex/em,
Abs 200-1000

FL 250-850,
Abs 200-1000

FL 250-850,
Abs 200-1000

FL 250-850
ex, 250-850 em;
Abs 200-1000

FL 250-850
ex, 360-850 em;
Abs 200-1000

230-750 

 340-650

Tunable
wavelength
(monochromators)

x

x

x

x

x

x

x

x

x

 

 

Endpoint

x

x

x

x

x

x

x

x

x

x

Kinetic

x

x

x

x

x

x

x

x

 

x

 

x

x

Spectral scanning

x

x

x

x

x

x

x

x

 

x

 

 

 

Well scanning

x

x

x

x

x

x

x

x

 

x

 

x

x

Microplate formats

6-1536 

6-1536

6-384+

6-384

6-384

6-384

6-384

6-384

6-384

6-1536

96-384

Fluidics

x

x

x++

 

 

 

 

 

 

 

 

Temperature control

x

x

x

x

x

x

x

x

x

x

 

Top reading

x

x

x

x

x

x

x

x

x

x

x

Bottom reading

x

x

x

x

x

x

x

x

 

x

 

Cuvette reading

x**

x**

 

x

x

x

x

x

x

 

 

Validation tools

x

x

x

x

x

x

x

x

x

 

 

Robotics / automation

x

x

x

x

x

x

x

x

x

x

x

 

All above trademarks are property of Molecular Devices, LLC
* Secondary modes
** Cuvette adaptor

+ 96- and 384-well with pipetting
++ 8- and 16-channel pipettors