GPCR Cell Lines: Biogenic Amines

FLIPR High Throughput Cellular Screening

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GPCR Cell Lines: Biogenic Amines

Acetylcholine

P/N	Sub-Type	Species	Validated Read-Outs
P/N	Sub-Type	Species	Calcium	cAMP	Binding
RCT6601	M1, CHO-K1	Human	•		•
RCT6102	M3, CHO-K1	Human	•		•
RA687	M4, CJO-K1	Rat		•	•
RCT6603	M5, CHO-K1	Human	•		•

Adrenergic

P/N	Sub-Type	Species	Validated Read-Outs
P/N	Sub-Type	Species	Calcium	cAMP	Binding
RA667	Alpha1a, CHO-K1	Human	•
RA663	Alpha2a, CHO-K1	Human		•	•
RA604	Alpha2b, CHO-K1	Human		•	•
RA664	Alpha2C, CHO-K1	Human		•	•
RA600	Beta2, CHO-K1	Human		•

Serotonin

P/N	Sub-Type	Species	Validated Read-Outs
P/N	Sub-Type	Species	Calcium	cAMP	Binding
RA601	5HT1a, CHO-K1	Human		•	•
RA659	5HT2b, CHO-K1	Human	•
RA660	5HT2b, CHO-K1	Mouse		•	•
RA661	5HT2c, CHO-K1	Human			•
RA605	5HT6, CHO-K1	Human			•