Ion Channel Cell Lines
For the best results, your ion channel assays require optimized and validated cell lines. But construction, optimization and validation of stable cell lines is labor, time and cost intensive. To eliminate this challenge, Molecular Devices, Inc. has partnered with ChanTest Corporation, a leading expert in ion channels, to distribute their extensive catalog of validated ion channel cell lines. Currently, there are more than 80 ion channel cell lines. Cells lines are provided as either replicating cell lines or frozen, ready-to-use EZCellsTM DA (division arrested) cells.
ChanTest has developed an extensive catalog of human ion channel expressing cell lines for drug discovery applications. Cells are validated for structure, function, and pharmacology. Performance is characterized using conventional patch-clamp and either the PatchXpress 7000A, IonWorks Quattro, or both. To minimize start-up time, the validation protocols for the PatchXpress and IonWorks are available.
EZCellsTM DA are validated, ready-to-use division-arrested cells that eliminate the need for lengthy pre-assay cell culture and processing. Like any reagent, EZCells are used once and discarded. Simply thaw, grow overnight, and run assays the next day. Uncouple cell culture from the screening process. EZCells are idea for screening or profiling studies and are batch-validated for consistent results. EZCells eliminates the need to maintain large numbers of cell lines. Purchase only what you need - when you need them. Cryopreserved in single-use vials, EZCells are fully functional and ready to use in screening and profiling assays.