Biological Assays

A bioassay (i.e., biological assay) is a procedure for the determination of the concentration of a particular constituent of a mixture or a measurement of the effects of a substance on living organisms.

They can measure the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. Examples of bioassays include the Limulus Test and endpoint determination.

The Limulus Test is a sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL) by the endotoxin or related compound. It is used for detection of endotoxin in body fluids and parenteral pharmaceuticals. Endpoint determination is an establishment of the level of a quantifiable effect indicative of a biologic process. This evaluation is frequently used to detect the degree of toxic or therapeutic effect of a drug or drug candidate.

Molecular Devices provides several bioassays and biological assays for drug discovery and drug development, and life science research. Please use the links below to learn more.

Threshold™ DNA Contaminant Detection Assay

Threshold™ Protein Contaminant Detection Assay

hERG test