Cellular Function

Cell Growth & Proliferation

The term cell growth is used in the contexts of cell development and cell division. When used in the context of cell division, it refers to growth of cell populations. In laboratories, cells are grown in culture. Cell proliferation is controlled by growth factors that bind to receptors on the cell surface that connect to signaling molecules that convey message from receptor to the nucleus where transcription factors bind to DNA, turning on or off the production of proteins that cause cells to continue dividing.

In the laboratory, cells are grown in cultures, dynamic populations that must be monitored frequently to identify changes in their conditions. Knowing the performance profile of your cell culture or primary cells prior to running your bioassay can mean the difference between valid assay results or wasted reagents, lost time, and discarded data. 

Profiling key cellular indicators, such as apoptotic fraction and stage of apoptosis, viability, cell cycle, cell counts, transfection efficiency, or target expression levels, will allow your lab to establish uniform standards of cellular performance. These standards can be applied to a wide range of bioassays.

Molecular Devices provides a range of bioanalytical systems to support your cell culture based research efforts, including products for basic microscopy and high- content imaging as well as microarray and microplate analysis products. Please use the links below to learn more.

MetaMorph® Microscopy Automation & Image Analysis Software

ImageXpress® High Content Screening Systems

ImageXpress® Velos Laser-Scanning Cytometer

GenePix® Microarray Scanners

SpectraMax® Microplate Readers